9/11/22 – Week 1 @ Washington Commanders – Wentz Exacts Revenge on Jaguars

9/18/22 – Week 2 Vs. Colts – Jaguars Blank Colts in Home Opener

9/25/22 – Week 3 @ L.A. Chargers – JAGUARS LIGHT UP CHARGERS IN LOS ANGELES; WIN SNAPS 18-GAME ROAD LOSING STREAK

10/2/22 – Week 4 @ Philadelphia – JAGUARS LET ONE SLIP AWAY IN PHILADELPHIA

10/9/22 – Week 5 @ Houston Texans – TEXANS TOPPLE JAGUARS, EARN FIRST WIN